For example, mesenchymal stem cells are purified from the entire bone marrow aspirate by removing cells expressing markers of individual types of cells, a step called enrichment with negative origin, <a href=https://residenzfestspiele.de/hello-world/>https://residenzfestspiele.de/hello-world/</a>, and then further separation of cells expressing the surface markers sca-1 and c-kit, indicating mesenchymal stem cells.